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产品目录

Huntingtin/HTT抗体图片
产品货号:
Z18478
中文名称:
Huntingtin/HTT抗体
英文名称:
Anti-Huntingtin/HTT Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-Huntingtin/HTT Antibody
指标别名HD;HD protein;HTT;huntingtin;Huntington disease protein;IT15
克隆性Polyclonal
检验物种human,mouse,rat
应用范围WB
基因名称HTT
抗体来源Rabbit
抗体类型IgG
免疫原A synthetic peptide corresponding to a sequence at the C-terminus of human Huntingtin(3106-3121aa ELDRRAFQSVLEVVAA),different from the related mouse and rat sequences by two amino acids.
实际分子量348KD
成分500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol.
纯化方式Immunogen affinity purified.
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料The huntingtin gene,also called HTT or HD(Huntington disease) gene,is the IT15("interesting transcript 15") gene which codes for a protein called the huntingtin protein.It is mapped to 4p16.3.The protein has no sequence homology with other proteins and is highly expressed in neurons and tests in humans and rodents.HTT upregulates the expression of Brain Derived Neurotrophic Factor(BDNF) at the transcription level,and this gene is required for normal development.The HTT protein is involved in vesicle trafficking as it interacts with HIP1,a clathrin-binding protein,to mediate endocytosis,the absorption of materials into a cell.HTT was also visualized as punctate staining likely to represent nerve endings.What's more,wildtype HTT may function in the nucleus in the assembly of nuclear matrix-bound protein complexes involved with transcriptional repression and RNA processing.
Uniprot IDP42858
推荐配套试剂Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。
基因名全称huntingtin
蛋白名全称Huntingtin
推荐稀释比
Western blot(WB) 1:500~2000

相关搜索:Huntingtin/HTT抗体Huntingtin抗体HTT多抗Anti-Huntingtin/HTT Antibody
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